Patient Centric Sampling – What it is and how it can transform decentralised clinical trials

The Patient Centric Sampling Interest Group (PCSIG) hosted an in-person one-day event on Sunday 2nd July, 2023, in Glasgow, Scotland, as a satellite meeting to the 19th World Congress of Basic & Clinical Pharmacology 2023 (#WCP2023).

The event discussed patient centric sampling (PCS) – the collection of high-quality samples for the determination of pharmacokinetic, pharmacodynamic and clinical chemistry endpoints. The technologies and workflows available to facilitate PCS offer the potential to collect high-quality samples from patients in settings away from centralized clinical locations, such as in the home. Thus, putting the needs of the patient at the center.

Follow the links below for presentations from experts from a range of stakeholders including pharma, healthcare, suppliers, and the patient voice.

Programme

1st Session – Chair David Sciberras, FBPhS

• Introduction to Patient Centric Sampling – Benefits and Technologies Available
  Ariane Kahnt (Janssen Research & Development, Belgium)
• Putting the Patient at the Centre
  Jenny Royle (MediPaCe, UK)
• Bioanalytical and Regulatory Considerations
  Chiara Rospo (UCB, Belgium)
• Use of Patient Centric Sampling in Clinical Trials & Public Health
  James Rudge (Trajan Scientific & Medical, UK)

Vendors Quick Fire Presentations

• ​Routine Adoption of Patient Centric Samples in the Analytical Laboratory
  Iain Love (Charles River Laboratories), UK
• Operational Considerations for Patient Centric Self-Collection
  John Corcoran (Q   Solutions, USA)
• Patient-Centric Sample Collection Enables Denser and More Resilient Data Collection in Clinical Trials
  Erwin Berthier (Tasso, IUSA)
• Utilizing microsampling to improve data, recruitment and diversity in clinical trials
  Minna Salonen (Trajan Scientific & Medical, Finland)
• Increasing participant engagement and completion with TAP blood collection technology
  Patricia Holman (YourBio Health, UK)

2nd Session – Chair James Rudge (Trajan Scientific & Medical, UK)

• Improving the Multiple Myeloma Patient Pathway: Microsampling for Remote Monitoring of Free Light Chains
  Nithya Paranthaman (The Royal Marsden Hospital, UK)
• Implementation of Volumetric Absorptive Microsampling Technology in Pediatric and Adult Drug Development Programmes
  Hugues Chanteux (UCB, Belgium)
• Implementing a patient-centric sampling strategy in the global clinical development of RSM01 (Anti-RSV mAb)
  Micha Levi (Gates MRI, USA)
• Thinking Patient Centricity: Reflections of a PCS case study
  Silvia Alonso Rodriguez (AstraZeneca, UK)